Title: The post-Rosetta era: New perspectives on nucleus composition and the role of radio and IR ground-based observations Abstract: Do ground-based observations of cometary comae describe the nucleus composition? Rosetta is allowing a unique opportunity to test this hypothesis. The space-based mission is unveiling incredible results, and its upcoming observations throughout perihelion promise to be the most detailed study yet of a comet. The significance of these studies is not trivial, and the results stemming from the expected worldwide observational campaign will trigger great involvement, including professional astrophysicists, amateur astronomers and the public. To enhance the outcome from past, present and future space-based missions, ground-based observations are a critical supporting strategy to put spacecraft results in context. It is through such synergy that we can establish the true means for quantitative detections on the study of comets, thanks to improved observational strategies, data analysis techniques and instrument performance. High-resolution spectroscopy at radio and infrared wavelengths provides measurements of the global properties of release and composition that can give context for Rosetta’s local measurements, allowing us to compare direct measurements of the nucleus to those inferred from ground-based observations of the coma. Indeed, extrapolation of the local measurements from the Rosetta spacecraft and ground-based observations can reveal essential coma information, including gas temperatures, production rates, and outgassing patterns as observed from the ground. Moreover, Rosetta''s lander Philae will measure the composition of the nucleus and that close to the surface. In this presentation, I will discuss unique aspects of cometary studies that can be solely achieved by ground-based radio and IR observations of the cometary comae, as well as benchmarks and challenges that we might need to address as a result of the Rosetta findings. Acknowledgements: NASA's Planetary Astronomy, Planetary Atmospheres and Astrobiology Programs, and the National Science Foundation. Co-authors: M.J. Mumma, G.L. Villanueva, B.P. Bonev, S.B. Charnley, M.A. Cordiner, M.A. DiSanti, E.L. Gibb, S.N. Milam